We start the video driving west on US-64 from the intersection with Arkansas Highway 7 in downtown Russellville. Driving west, we soon cross Lake Dardanelle and Arkansas Nuclear 1 as we make our way into London before turning north to cross under Interstate 40 as we travel towards Lamar and Clarksville. At Arkansas Highway 21, US-64 turns west to cross I-40 again west of Clarksville
Continuing west, we soon reach Altus and Ozark, where we cross the intersection with the Pig Trail Scenic Byway (AR-23). Leaving Ozark, we soon reach Mulberry where we continue west on US-64 towards Alma, where we end the video at the intersection with U.S. Highway 71 Business.