Drive America’s Highways for 128 miles west along Interstate 22 from Birmingham to Tupelo.
Interstate 22
Interstate 22 is a 202.5-mile-long Interstate Highway in the US states of Mississippi and Alabama, connecting I-269 near Byhalia, Mississippi, to I-65 near Birmingham, Alabama. I-22 is also Corridor X of the Appalachian Development Highway System.
Designated in 2012, I-22 follows the route of the older U.S. Route 78 (US 78). The freeway mainly spans rural areas and passes numerous small towns along its route, including Fulton, Tupelo, New Albany, and Holly Springs in Mississippi; and Jasper, Winfield, and Hamilton in Alabama.
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![[Revisited] Interstate 22: Tupelo to Birmingham – Mississippi/Alabama](http://interstate411.us/wp-content/uploads/2024/09/p49_zamwykgmaxresdefault-400x250.jpg)
[Revisited] Interstate 22: Tupelo to Birmingham – Mississippi/Alabama
Drive America’s Highways for 128 miles east along Interstate 22 from Tupelo to Birmingham.
Interstate 22: Tupelo Mississippi to Birmingham Alabama
Drive America’s Highways for 127 miles east along Interstate 22 from Tupelo, Mississippi to Birmingham, Alabama.
Interstate 22: Memphis to Tupelo – Mississippi
Drive America’s Highways for 76 miles east along Interstate 22 from Memphis to Tupelo in Mississippi.