Interstate 22: Memphis to Tupelo – Mississippi

🚙 Drive America’s Highways for 76 miles east along Interstate 22 from Memphis to Tupelo in Mississippi.

We start the video at a cloverleaf interchange with Interstate 269 at the western terminus of Interstate 22 in Byhalia, just southeast of Memphis. Driving generally southeast (into the morning sun, our apologies — it get’s better), we pass through Victoria and Red Banks before reaching Holly Springs, where we cross the interchange with MS-7 and MS-4. Continuing on Interstate 22 towards Tupelo, we pass through Holly Springs National Forest, with interchanges at Potts Camp and Hickory Flat.

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Leaving Holly Springs National Forest at Myrtle, we stay on I-22 through New Albany, passing interchanges with MS-30 and MS-15. Leaving New Albany heading southeast, we pass through Blue Springs and Sherman before reaching Tupelo. Driving through the north side of Tupelo, we cross the Natchez Trace Parkway and a cloverleaf interchange with U.S. Highway 45 before ending the video leaving I-22 at exit 87 – Veterans Memorial Blvd.


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