Interstate 22: Memphis to Tupelo – Mississippi

🚙 Drive America’s Highways for 76 miles east along Interstate 22 from Memphis to Tupelo in Mississippi.

We start the video at a cloverleaf interchange with Interstate 269 at the western terminus of Interstate 22 in Byhalia, just southeast of Memphis. Driving generally southeast (into the morning sun, our apologies — it get’s better), we pass through Victoria and Red Banks before reaching Holly Springs, where we cross the interchange with MS-7 and MS-4. Continuing on Interstate 22 towards Tupelo, we pass through Holly Springs National Forest, with interchanges at Potts Camp and Hickory Flat.

Leaving Holly Springs National Forest at Myrtle, we stay on I-22 through New Albany, passing interchanges with MS-30 and MS-15. Leaving New Albany heading southeast, we pass through Blue Springs and Sherman before reaching Tupelo. Driving through the north side of Tupelo, we cross the Natchez Trace Parkway and a cloverleaf interchange with U.S. Highway 45 before ending the video leaving I-22 at exit 87 – Veterans Memorial Blvd.


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