Drive America’s Highways for 22 miles north along Interstate 57 from Sikeston to Illinois.

We start the video merging onto Interstate 57 at it’s western terminus at Interstate 55 just south of Sikeston, Missouri. Travelling generally east in Missouri, we cross the interchange with Missouri Highway 105 in Charleston (tip: last decent stop before Marion is here…Also, if you smoke, I hear they have cheap cigarettes at one of the stops at this location.)

Turning northeast, we cross an interchange with U.S. Highway 62 (to Cairo, Illinois and Sikeston) before reaching the Mississippi River and the end of our video at the Illinois State Line