Interstate 40 – Mile 402 to Mile 421 – Tennessee

America’s Highways for 19 miles along Interstate 40 from mile 402 to mile 421 in Tennessee.

We start the video leaving the Knoxville metro, just past the Midway Road exit (402) heading east on Interstate 40 towards Asheville, NC.

Along the way we cross the junction with Tennessee State Highway 66, which will take you down to Pigeon Forge and Gatlinburg, and U.S. Highway 25W. At US-25W, we make a brief fuel stop and return to Interstate 40 east to the Interstate 81 interchange at mile 421, where we turn left onto Interstate 81.



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