We start the drive along eastbound Interstate 70 in Columbus at the junction with the Outerbelt – Interstate 270 – on the west side of town. Driving generally east, we pass a few local interchanges before reaching the interchange with Interstate 670, just west of downtown Columbus. Continuing eastbound on 70, we enter downtown at an interchange with U.S. Highway 40.
Passing through the south side of downtown Columbus, we cross the interchange with U.S. Highway 62 before reaching the junction with Interstate 71 south. Staying on I-70, we enter a construction zone as ODOT rebuilds the I-71 north interchange. Leaving downtown Columbus as we exit the construction zone, we turn briefly southwest to cross the interchange with U.S. Highway 33 – the Southeast Expressway.