We start the drive from Kennett, Missouri to Paragould, Arkansas driving southwest on U.S. Route 412 from the intersection with Missouri Route 84 in Kennett. Continuing southwest through town, we pass the roundabout with Missouri Supplemental route VV as we make our way out of Kennett towards Senath. Turning briefly south and then west to bypass Senath to the southeast, we continue southwest on US-412. Passing the junction with MO-108, we pass between Arbyrd and Cardwell. Just past the intersection with MO-164, we turn west to pass Cardwell on the south before turning northeast to cross the St. Francis River and enter Arkansas.
Entering Arkansas, we pass the southern terminus of AR-139 before turning west once again. Traveling approximately 4 miles, we enter Paragould from the east, passing through light agriculture-based industry and associated commercial businesses. At the junction with U.S. Highway 412B, we continue straight onto US-412B while US-412 bypasses Paragould to the south.
Now on US-412B, we continue west into Paragould, crossing the intersection with Arkansas Highway 69 as we drive closer to the center of town. As we reach the crossroads of town — the intersection with U.S. Highway 49 — we end the video at the crossroads waiting on a stoplight.